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MTHFR Support is specially formulated by a physician and is part of Raffaele Medical proprietary Blends product line. This blend of ingredients contains a specialized combination of ingredients designed to address nutritional deficiencies commonly found today. This synergistic formula uses folate as (6S)-5-methyltetrahydrofolic acid, glucosamine salt which is a highly bioavailable form of naturally-occurring folate. Folate has been shown to play a crucial role in DNA and RNA synthesis as well as contributing to healthy function of the central nervous system and immune system. This formula also contains a combination of B vitamins, including Pantothenic Acid, B6 and B12. Pantothenic acid is involved in synthesizing energy, fatty acid synthesis, and oxidation. The Vitamin B6 used in this formula contains P-5-P which is the most biologically active form of B6, it also includes pyridoxine HCL. As a co-factor for more than 50 different enzymes, Vitamin B6 is involved in key metabolic activities. Finally, vitamin B12 Methylcobalamin is the active form of B12 which plays a key role in homocysteine metabolism, red blood cell formation, and may contribute to healthy function of the nervous and immune systems. *