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Vitamin B12 and folate are synergistic nutrients that play an integral role in nervous system function, macronutrient metabolism, and gastrointestinal function. Additionally, folate is essential for healthy fetal neural development and the synthesis of DNA and RNA. Supplementation with either folate or B12 alone can often increase requirements of the other nutrient, so it is highly recommended that both vitamins be supplemented simultaneously. Raffaele Medical Folate-B12 is a high potency, capsule that combines 1mg of the active coenzyme form of B12, methylcobalamin, with the 800mcg of the active form of folate, Metafolin® L-5 methyltetrahydrofolate. *