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Alpha lipoic acid, an antioxidant itself, is integral in the induction of glutathione synthesis; an important intracellular antioxidant that decreases with age. Additionally, in vitro studies have demonstrated that alpha lipoic acid modulates normal insulin action, thus supporting healthy glucose metabolism. In addition to insulin signaling, alpha lipoic acid potentiates other cell signaling molecules that play important roles in hepatic health and normal vasodilation. Oral alpha lipoic acid supplements are better absorbed on an empty stomach and should be taken 1-2 hrs before a meal. *